Areejit Samal
Reader
Computational Biology
2254 3219
asamal @ imsc . res . in
219 New Building
Research Interests:
- Network theory
- Systems biology
- Metabolic networks
- Gene regulatory networks
- Next Generation Sequencing datasets
- Knowledgebases for drug discovery
- Statistical Genetics
Education:
- Ph.D. Physics, University of Delhi, Delhi (2009)
- M.Sc. Physics, University of Delhi, Delhi (2003)
- B.Sc. (H) Physics, Ramjas College, University of Delhi, Delhi (2001)
Career History:
- Faculty Member, The Institute of Mathematical Sciences (IMSc), Chennai (2014 - )
- Senior Postdoctoral Fellow, International Centre for Theoretical Physics (ICTP), Trieste, Italy (2013-2014)
- Postdoctoral Fellow, Institute for Systems Biology, Seattle, USA (2012-2013)
- CNRS-MPG Joint Program in Systems Biology Fellow, LPTMS, Univ Paris-Sud 11, Orsay, France & Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany (2010-2012)
- FEBS Short Term Fellow, Univ Paris-Sud 11, Orsay, France (2009)
- Postdoctoral Fellow, Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany (2008-2010)
Courses Taught:
- Biology-1 course in the Computational Biology PhD program
- Biology-2 course in the Computational Biology PhD program
Selected publications:
- Comparative analysis of two discretizations of Ricci curvature for complex networks, A. Samal#, R.P. Sreejith#, J. Gu, S. Liu, E. Saucan* & J. Jost*, Scientific Reports 8: 8650 (2018).
- Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species, R.P. Vivek-Ananth, K. Mohanraj, M. Vandanashree, A. Jhingran, J.P. Craig & A. Samal*, Scientific Reports 8: 6617 (2018).
- Network approach towards understanding the crazing in glassy amorphous polymers, S. Venkatesan#, R.P. Vivek-Ananth#, R.P. Sreejith, P. Mangalapandi, A.A. Hassanali* & A. Samal*, Journal of Statistical Mechanics: Theory and Experiment 043305 (2018).
- IMPPAT: A curated database of Indian Medicinal Plants, Phytochemistry and Therapeutics, K. Mohanraj#, B.S. Karthikeyan#, R.P. Vivek-Ananth#, R.P. Bharath Chand, S.R. Aparna, P. Mangalapandi & A. Samal*, Scientific Reports 8:4329 (2018).
- Network Reconstruction And Systems Analysis Of Plant Cell Wall Deconstruction By Neurospora crassa, A. Samal, J.P. Craig, S.T. Coradetti#, J.P. Benz#, J.A. Eddy, N.D. Price* & N.L. Glass*, Biotechnology for Biofuels 10:225 (2017).
- Forman curvature for complex networks, R.P. Sreejith, K. Mohanraj, J. Jost, E. Saucan & A. Samal*, Journal of Statistical Mechanics: Theory and Experiment 063206 (2016).
- Statistical physics methods provide the exact solution to a long-standing problem of genetics, A. Samal & O.C. Martin*, Physical Review Letters, 114: 23801 (2015).
- Phenotypic constraints promote latent versatility and carbon efficiency in metabolic networks, M. Bardoscia, M. Marsili & A. Samal*, Physical Review E 92: 012809 (2015).
- Network function shapes network structure: the case of the Arabidopsis flower organ specification genetic network, A. Henry, F. Monéger, A. Samal* & O.C. Martin*, Molecular Biosystems 9(7):1726-1735 (2013).
- Environmental versatility promotes modularity in genome-scale metabolic networks, A. Samal, A. Wagner* & O.C. Martin*, BMC Systems Biology 5:135 (2011).
- Randomizing genome-scale metabolic networks, A. Samal & O.C. Martin*, PLoS ONE 6(7):e22295 (2011).
- Genotype networks in metabolic reaction spaces, A. Samal, J.F. Matias Rodrigues, J. Jost, O.C. Martin* & A. Wagner*, BMC Systems Biology 4:30 (2010).
- The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of response, A. Samal & S. Jain*, BMC Systems Biology 2:21 (2008).
- Low degree metabolites explain essential reactions and enhance modularity in biological networks, A. Samal, S. Singh, V. Giri, S. Krishna, N. Raghuram & S. Jain*, BMC Bioinformatics 7:118 (2006).
(#Equal contribution *Corresponding author)